Chemotherapy Gloves

chemo gloves & chemotherapy gloves for cleanroom use

Chemotherapy Gloves & Sterile Chemo Gloves

Chemotherapy gloves are specifically tested to resist permeation by chemotherapy drugs and help protect personnel during hazardous drug compounding, administration, transport, and cleanup activities. Healthcare workers, pharmacists, and pharmacy technicians handling hazardous drugs require gloves that provide a higher level of protection than standard examination gloves.

USP <800> recommends the use of chemotherapy-tested gloves whenever handling hazardous drugs. These gloves are commonly manufactured from nitrile materials and undergo ASTM D6978 testing to verify resistance against a range of chemotherapy agents. Available in sterile and non-sterile configurations, chemotherapy gloves help reduce exposure risks while supporting compliance with workplace safety standards.

Cleanroom Connection offers a wide selection of chemotherapy gloves from trusted manufacturers including Halyard, CT International, Kimberly-Clark, and PureZero. Whether you require sterile gloves for cleanroom compounding or extended-cuff chemotherapy gloves for additional protection, our selection provides dependable hand protection for pharmacy, healthcare, laboratory, and oncology applications.

Chemotherapy Gloves vs Standard Nitrile Gloves

While many nitrile gloves provide excellent protection for general laboratory and healthcare applications, chemotherapy gloves undergo additional testing to verify their resistance to hazardous drug permeation. The table below highlights the key differences.

Feature Chemotherapy Gloves Standard Nitrile Gloves
Intended Use Hazardous drug handling General protection
USP 800 Compliance Recommended for hazardous drugs Not automatically compliant
ASTM D6978 Tested Yes Usually No
Chemotherapy Drug Resistance Verified through testing Not verified
Hazardous Drug Handling Recommended Not recommended
Pharmacy Compounding Recommended Limited
Oncology Applications Recommended Limited
Sterile Options Available Yes Some models
Extended Cuff Options Common Less common
Cleanroom Compatibility Available for ISO cleanrooms Varies by product
Chemical Permeation Testing Required Not typically performed
Level of Protection High Moderate

Why USP 800 Requires Chemotherapy Gloves

USP <800> recommends chemotherapy gloves whenever handling hazardous drugs because exposure can occur through direct skin contact with contaminated surfaces, containers, or medications. Chemotherapy gloves are tested to ASTM D6978 standards to verify resistance to chemotherapy drug permeation and provide a higher level of protection than standard examination gloves.

Available in sterile and non-sterile configurations, chemotherapy gloves help support USP <800> compliance while protecting pharmacists, technicians, nurses, and healthcare workers during hazardous drug compounding, administration, and cleanup activities.

Types of Chemotherapy Gloves

Glove Type Best Application
Sterile Chemotherapy Gloves Sterile compounding and cleanrooms
Non-Sterile Chemotherapy Gloves Drug receiving and administration
Extended Cuff Chemotherapy Gloves Additional wrist and forearm protection
Cleanroom Chemotherapy Gloves ISO classified environments
Accelerator-Free Chemotherapy Gloves Users with chemical sensitivities
Double-Gloving Systems High-risk hazardous drug handling

image representing purple nitrile glove halyard marin glove

* PureZero Marin Nitrile Lab Glove

Halyard PureZero Marin purple nitrile gloves are our most popular non-sterile lab glove. These gloves are not for use in ISO5 Class 100 clean rooms since they come boxed, however they are chemo-rated and suitable for use in less strict ISO7-8 clean rooms. Many customers use these purple nitrile gloves as their non-sterile chemo gloves. They come in both 9 inch and 12 inch lengths. There are 500 gloves per case on the 12″ and 1000 gloves per case on the 9″. These are our most poplar non-sterile nitrile chemo-rated lab glove.

    • Non-Sterile
    • Same glove as Kimberly Clark purple nitrile
    • Economical
    • Powder-free
    • Sizes small through XL
    • Choose 9.5″ or 12″ length
    • ASTM D6978-05 chemo tested
    • USP 800 compliant
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cti nsgf nitrile sterile cleanroom gloves

CTI NSGF Nitrile Sterile Cleanroom Gloves

CTI NSGF sterile nitrile surgical cleanroom gloves are made from 100% nitrile with no latex proteins. They are 12 inches long and made for use in ISO5 Class 100 environments. They are chemo-rated and come in individually wrapped pair. These are our most popular sterile nitrile cleanroom glove due to the economical price, bisque-textured grip, and surgical style fit which is great for handling small objects.

    • Most requested sterile glove
    • Sizes from 6.0 – 10.0
    • 200 Pairs Per Case
    • Class 100 ISO5
    • Bisque textured finish
    • 12″ length for good wrist coverage
    • Sterile
    • ASTM D6978-05 Chemo Rated
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haylard purezero sterile blue nitrile cleanroom glove

Halyard PUREZERO Blue Nitrile Sterile Cleanroom Glove

PUREZERO HG3 Blue Sterile Nitrile Cleanroom Gloves are designed for critical cleanroom environments such as pharmaceutical and biotechnology cleanroom manufacturing as well as sterile compounding cleanroom applications. These hand-specific gloves are cleaned and processed (washed repeatedly in deionized water) to ensure consistent control of low particles, extractables, and endotoxin levels. They are recommended for use in ISO Class 3 or higher and Grade A/B cleanrooms. The are accelerator-free to eliminate any skin irritation.

    • Sterile
    • Preferred over Kimtech Sterling sterile nitrile glove
    • Great pricing
    • Thinner 3.9 mil thickness
    • Sizes from 6.0 – 10.0
    • 300 Pairs Per Case, 12″ length
    • Class 10-100 ISO3-5
    • Anti-static & Accelerator-free
    • ASTM D6978-05 Chemo-Rated
    • Great for double gloving, blue under white
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haylard purezero sterile nitrile cleanroom glove

Halyard PUREZERO Nitrile Sterile Cleanroom Glove

PUREZERO HG3 White Sterile Nitrile Cleanroom Gloves are designed for critical cleanroom environments such as pharmaceutical and biotechnology cleanroom manufacturing as well as sterile compounding cleanroom applications. These hand-specific gloves are cleaned and processed (washed repeatedly in deionized water) to ensure consistent control of low particles, extractables, and endotoxin levels. They are recommended for use in ISO Class 3 or higher and Grade A/B cleanrooms. The are accelerator-free to eliminate any skin irritation.

    • Sterile
    • Preferred over Kimtech G3 sterile nitrile glove
    • Great pricing
    • 6.3 mil standard thickness
    • Sizes from 6.0 – 10.0
    • 200 Pairs Per Case
    • Class 10-100 ISO3-5
    • Anti-static & accelerator-free
    • 12″ length for good wrist coverage
    • ASTM D6978-05 Chemo-Rated
    • USP 800 compliant
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handpro fortis 500 extended cuff nitrile lab glove

HandPro Fortis 500 Extended Cuff Nitrile Lab Glove

HandPRO Fortis 500 Extended Cuff Powder-Free Nitrile Exam Gloves are created from the latest patented accelerator-free Low Derma nitrile. The nitrile lab gloves are chemotherapy-rated, and fentanyl-rated making them great for hazardous drug handling. The extended 10.5″ cuff also protects more of your forearm. Fortis 500 lab gloves are thicker than typical exam gloves for increased puncture and abrasion resistance, and features an extended cuff for extra wrist and forearm protection in demanding, high-risk environments. These nitrile lab gloves contain no dithiocarbamates,thiurams or mercaptobenzothiazoles (MBT), or thiurams and are manufactured with no sulfur added.

    • Sizes from XS-XXL
    • 100 gloves per box, 10 boxes per case
    • ASTM D6978-05 chemotherapy rated
    • Fentanyl & Xylazine tested
    • Double-donnable, USP 800 compliant
    • NFPA1999 Compliant for high risk environments
    • Accelerator free & powder-free
    • 10.5″ extended cuff length
    • Non-Sterile
    • Anti-static, finger-textured
    • Matte black color
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handpro freestyle 1100 purple nitrile lab glove

HandPro Freestyle 1100 Purple Nitrile Lab Glove

HandPRO FreeStyle1100™ Nitrile Lab Exam Gloves are accelerator free, ensuring low dermatitis potential, and are highly flexible and conform to the hand. They offer superior flexibility and freedom of hand movement. These lab gloves are chemotherapy-rated and USP 800 compliant. They are latex-free, powder-free glove, and have the fewest chemicals in their composition to avoid Type I latex and Type IV chemical allergic reactions. This unique nitrile formulation sheds liquids better for a more secure grip – even in wet environments. These nitrile lab gloves are made with patented Low Derma™ accelerator-free nitrile, and contain no dithiocarbamates,thiurams or mercaptobenzothiazoles (MBT), and are sulfur & thiuram-free.

    • Sizes from XXS-XXL
    • 100 gloves per box, 10 boxes per case
    • ASTM D6978-05 chemotherapy rated
    • Fentanyl & Xylazine tested
    • Double-donnable
    • 510k rated
    • Accelerator free, powder-free
    • 9.5″ extended cuff length
    • Non-Sterile
    • Anti-static, finger-textured
    • Violet blue color
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haylard purezero sterile blue nitrile cleanroom glove

Haylard PUREZERO Blue Nitrile Cleanroom Glove

PUREZERO HG3 Blue Nitrile Cleanroom Gloves are designed for critical cleanroom environments such as pharmaceutical and biotechnology cleanroom manufacturing as well as non-sterile compounding cleanroom applications. These hand-specific gloves are cleaned and processed (washed repeatedly in deionized water) to ensure consistent control of low particles, extractables, and endotoxin levels. They are recommended for use in ISO Class 3 or higher and Grade A/B cleanrooms. The are accelerator-free to eliminate any skin irritation.

    • Non-sterile
    • Light blue color
    • Tacky grip
    • XS to XL sizes
    • 1500 gloves, 6 bags of 250pcs
    • Class 10-100 ISO3-5
    • Anti-static
    • Accelerator-free
    • 12″ length for good wrist coverage
    • ASTM D6978-05 Chemo-Rated
    • USP 800 compliant
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haylard purezero sterile nitrile cleanroom glove

Haylard PUREZERO Nitrile Cleanroom Glove

PUREZERO HG3 White Nitrile Cleanroom Gloves are designed for critical cleanroom environments such as pharmaceutical and biotechnology cleanroom manufacturing as well as non-sterile compounding cleanroom applications. These hand-specific gloves are cleaned and processed (washed repeatedly in deionized water) to ensure consistent control of low particles, extractables, and endotoxin levels. They are recommended for use in ISO Class 3 or higher and Grade A/B cleanrooms. The are accelerator-free to eliminate any skin irritation.

    • Non-sterile
    • XS to XL sizes
    • Tacky grip
    • 1000 gloves, 10 bags of 100
    • Class 10-100 ISO3-5
    • Anti-static
    • Accelerator-free
    • 12″ length for good wrist coverage
    • ASTM D6978-05 Chemo-Rated
    • USP 800 compliant
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kimtech g3 sterile cleanroom gloves

KimTech G3 Nitrile Sterile Cleanroom Glove

Kimberly Clark Kimtech G3 sterile nitrile cleanroom gloves are one of our best selling gloves. These gloves are 12 inches, powder-free, latex-free, clean-processed and even USP 800 compliant for working with cytoxic drugs including chemotherapy solutions. These sterile Kimtech G3 nitrile gloves are chemo-rated making it very convenient to use one glove for many purposes. There are 200 sterile, individually packed pairs per case. These gloves come with all the necessary sterility paperwork and certificates. The Kimtech G3 nitrile sterile glove is also anti-static treated and tested.

    • Sizes from 6.0 – 10.0
    • 200 Pairs Per Case
    • Class 10-100 ISO3-5
    • Anti-static
    • 12″ length for good wrist coverage
    • Sterile
    • ASTM D6978-05 Chemo-Rated
    • USP 800 compliant
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