Sterile Cleanroom Wipes for Critical Environments
Sterile cleanroom wipes are essential for maintaining contamination control in critical environments. Designed for low particle generation and high absorbency, these wipes are sterilized and packaged to meet the strict requirements of ISO-classified cleanrooms. Commonly used for surface cleaning, equipment wipe-downs, and disinfectant application, sterile wipes help reduce particulate and microbial contamination in sensitive manufacturing and laboratory settings.
Sterile wipes are available in a variety of materials including polyester, nonwoven, and microfiber, and can be dry or pre-saturated with sterile solutions such as isopropyl alcohol, hydrogen peroxide, or other disinfectants. These wipes are widely used in pharmaceutical, biotechnology, and medical device cleanrooms where aseptic conditions are required. Whether used for routine cleaning or critical process support, sterile cleanroom wipes play a key role in maintaining compliance with USP <797>, USP <800>, and cGMP standards.
Choosing the Right Sterile Wipe Material
- Polyester → Lint-free, durable, scrubbing, solvent compatible
- Microfiber → Lint-free, deep cleaning, picks up 99% particles
- Nonwoven → Extreme low-linting, economical, general wiping
- Polypropylene → Lint-free, chemical compatibility, durable
- 70% IPA Presaturated → Convenient, available in multiple materials
Sterile Cleanroom Wipe Uses by Industry
- Sterile cleanroom wipes are used across critical industries where maintaining low particulate levels and microbial control is essential for product quality and regulatory compliance.
| Industry | Common Use | Why Sterile Wipes Are Used |
|---|---|---|
| Pharmaceutical Manufacturing | Aseptic processing, equipment cleaning | Maintains sterile conditions and supports USP <797>/<800> compliance |
| Biotechnology | Lab surfaces, process equipment | Reduces contamination risk in sensitive biological processes |
| Medical Device Manufacturing | Assembly and packaging areas | Prevents particulate contamination on finished products |
| Compounding Pharmacies | Buffer rooms and cleanrooms | Required for sterile compounding environments |
| Laboratories | Surface cleaning and prep areas | Ensures consistent cleanliness and contamination control |
| Semiconductor / Electronics | Precision cleaning of components | Minimizes particles that can cause defects |
Biomedix Lint-Free Sterile Cleanroom Wipe
TrueCare sterile lint free cleanroom wipes are our customers’ favorite sterile dry cleanroom wiper. They are super absorbent, extra durable, and economical. Accompanied by a certificate assuring gamma sterilization. These wipes are widely are used in medical device manufacturing, USP compounding pharmacies, as well as cGMP pharmaceutical manufacturing.
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- Sterile
- Nonwoven blend of 55% cellulose and 45% polyester
- Most popular sterile lint-free wipe
- 9″x9″, 12 bags of 300 or in 180 bags of 20
- 12″x12″, 8 bags of 150 or in 60 bags of 20 wipes
- Class 1000 ISO6+
Biomedix Sterile 4×4 Nonwoven Alcohol Wipe
True Care TCBWALC6004 sterile isopropyl alcohol cleanroom wipes are lint-free and safe for use in your ISO5+ critical environments. These wipes are 4″x4″ which is an efficient size for cleaning vials and small items. They are made of ultra-clean nonwoven polyester which has a smooth cloth texture, is lint-free and extremely durable.
- Sterile
- 4″x4″ size
- Nonwoven polyester
- 70% USP Grade IPA / 30% DI water
- 1440 wipes, 24 pouches of 60 wipes
- Class 100 ISO5+ compatible
- Thicker than other pre-wetted wipes for added durability and absorption
- Tear proof, soft cloth texture will not scratch any surfaces
Biomedix Sterile 4×4 Polyester Alcohol Wipe
True Care TCBWALC1204 sterile isopropyl alcohol cleanroom wipes are lint-free and safe for use in your ISO4-5 critical environments. These wipes are 4″x4″ which is an efficient size for cleaning vials and small items. They are made of ultra-clean polyester which has a smooth cloth texture, is lint-free and extremely durable.
- Sterile
- 4″x4″ size
- 70% USP Grade IPA / 30% DI water
- 1440 wipes, 24 pouches of 60 wipes
- Class 10-100 ISO4-5 compatible
- Thicker than other pre-wetted wipes for added durability and absorption
- Tear proof, soft cloth texture will not scratch any surfaces
BioMedix Sterile Alcohol Wipe
True Care Sterile 70% IPA presaturated cleanroom wipes are our top selling sterilized presaturated cleanroom wipe. The nonwoven wipe is presaturated with sterile 70% isopropyl alcohol, 30% DI water and measures 9 inches by 9 inches. They come in thick plastic pouches with a plastic spring hinged side door that seals shut automatically. You open the door, remove a wipe and the door closes. Each pouch comes double bagged.
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- Most popular sterile prewetted cleanroom wipe
- Prewetted with 70% IPA / 30% DI water
- 9″x9″ Size
- 720 wipes, 24 packs of 30 wipes
- Class 1000 ISO6 and higher rated
- Ready to use, saturated
- Sterile
- Plastic bag door automatically closes
Kimtech 76490 Sterile Alcohol Wipe
Kimberly Clark KimTech 76490 sterile presaturated cleanroom wipes are lint-free and safe for use in your ISO4-5 critical environments. These wipes are 9″x11″ which is an efficient size for cleaning and disinfecting surfaces. Their polypropylene blend material is cleaner than other sterile nonwoven presaturated wipes.
- 9″x11″ size
- Prewetted with sterile 70% IPA / 30% DI water
- 400 sterile wipes, 10 bags of 40
- Class 10+ ISO4 compatible
- Thicker than other pre-wetted wipes for added durability and absorption
- Non-shedding, ultra-clean
PurWipe K1 Polyester Sterile Cleanroom Wipe
PurWipe K1 sterile double-knit polyester cleanroom wipes are high quality with sealed edges for the lowest particle emission for use in ISO4 Class 10 clean rooms or higher. They are suitable for diverse applications in stricter controlled environments. The extra-strong double knit polyester which is fully sterilized and lint-free, boasts a high fluid absorption rate, and is exceptional for scrubbing, even abrasive surfaces. 1000 wipes per case, 100 bags of 10 wipers.
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- Sterile
- Lint-free
- 9″x9″
- Ultra-clean Class 10 ISO4+
- Durable double knit polyester material
- Sealed edges
- Triple-bagged inside a cleanroom
- Laundered and clean-processed
- 100 bags of 10 wipes per case
- Lot-specific certificate of sterility and analysis
PurWipe N1 Nonwoven Sterile Cleanroom Wipe
PurWipe N1 sterile lint-free wipes are constructed from a hydroentangled nonwoven material. The highly absorbent polycellulose wipe is well suited for disinfection, absorption of spillage, or general cleanroom cleaning. Its economic price and durability make it a go-to wipe for a broad range of applications in less strict cleanrooms. There are 100 bags of 20 wipes per case.
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- Sterile
- Non-shedding
- Great for general wiping and cleanroom cleaning
- 9″x9″
- For use in Class 100 ISO5 and higher
- Lot-specific certificate of sterility and analysis
- Triple-bagged inside a cleanroom environment
- 100 bags of 20 wipes per case, 2000pcs
PurWipe N2 Microfiber Sterile Cleanroom Wipe
PurWipe N2 sterile microfiber cleanroom wipes are a state-of-the-art wipe made of 100% synthetic polyamide fibers. They are the cleanest nonwoven wipe we offer suitable for ISO5 Class 100 and cGMP critical environments. The N2 sterile wipe offers high fluid absorption combined with reduced particle emission. This sterile wipe‘s small microfibers cling to the smallest of particles ensuring effective and efficient cleaning for all cleanroom surfaces. The synthetic microfiber is resistant to tearing and abrasion. Case of 2000 wipes, 100 bags of 20 wipes.
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- Sterile
- Lint-free
- Cleaner than other nonwoven wipes
- Tear-resistant, abrasion-resistant
- 9″x9″
- Suitable for Class 100 ISO5
- Lot-specific certificate of sterility & analysis
- Triple-bagged in a cleanroom
- 100 bags of 20 wipes per case, 2000 pcs
TekniClean Sterile Alcohol Wipe
Teknipure TekniClean ultra-clean sterile polyester presaturated cleanroom wipers are pre-wetted with 70% isopropyl alcohol and 30% DI water. These wipes are manufactured using ultra-clean polyester material. Compatible with ISO4 Class 10+ extra critical environments. Polyester presaturated cleanroom wipes are the cleanest of all prewetted 70% IPA 30% DI water wipes.
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- Sterile
- 9″x9″ size
- Ultra-clean polyester
- ISO4 Class 10 compatible
- 40 wipes per pack, 24 packs per case
- Prewetted with 70% IPA / 30% DI water
- Suitable for the most critical surfaces and areas
TekniPolyPro Sterile Alcohol Wipe
Teknipure TekniPolyPro polypropylene presaturated cleanroom wipers are pre-wetted with 70% isopropyl alcohol and 30% DI water. These wipes are fully synthetic and made of 3-layer meltblown polypropylene which is durable, abrasion-resistant and very clean. Compatible with ISO5 Class 100 environments. These wipes are a great alternative to the Kimtech 76490 sterile presaturated cleanroom wiper.
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- Sterile or non-sterile
- 9″x11″ size
- 3-layer
- ISO5 Class 100 compatible
- 1200 wipes per case, 24 packs of 50
- Polypropylene material
- Prewetted with 70% IPA / 30% DI water
- Great for deep cleaning or scrubbing
VAI Process-2-Wipe Sterile Alcohol Wipe
VAI Veltek Process2Wipe presaturated sterile lint-free cleanroom wipers are pre-wetted with 70% isopropyl alcohol and 30% WFI water. These wipes are manufactured using ultra-clean polyester material, the cleanest of all wipe materials. Compatible with ISO4 Class 10+ extra critical environments, these wipes are recommended for the strictest cleaning jobs.
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- Sterile
- 9″x9″ or 12″x12″ size
- Ultra-clean polyester
- Peel & reseal pouch or zip-lock style option
- 70% IPA, 30% WFI water
- ISO4 Class 10 and higher compatible
- Suitable for the most critical surfaces and areas
VAI WipeDown Sterile Wipe
VAI WipeDown sterile dry polyester cleanroom wipes are an ultra-clean, superior, laundered dry wipe suitable for use in a cleanroom environment. These sterile polyester dry wipes are ideal for use in both aseptic and non-septic wipe downs of filling and packaging machinery, stainless steel surfaces, lexan, polycarbonate, glass, and any critical surface that requires cleaning. They are a great wiping solution that will keep your surface dry, residue free, and streak free after chemical application. These wipes are a generous 12″x12″ size, coming in cases containing 30 bags of 20 wipes. The wipes are packaged in easy-tear, clear, cleanroom bags.
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- Sterile
- Soft cloth texture
- 100% continuous knit polyester filament
- Ultra-soft for sensitive surfaces
- Lint-free
- 12″x12″
- Ultra-clean ISO4-5 Class 10-100 rated
- Specially sealed FocusEdge edges
- 30 bags of 20 wipes per case
- Lot-specific certificate of sterility and analysis