Cleanroom Wipes | Sterile, Lint-Free Wipes
Cleanroom wipes are essential for maintaining contamination control in controlled environments where particulate, microbial, and chemical cleanliness must be tightly managed. Used across pharmaceutical compounding, biotechnology, medical device manufacturing, and electronics production, these lint-free wipes support cleaning and disinfection protocols in ISO-classified cleanrooms and critical environments. Whether for routine surface cleaning or sterile processing applications, selecting the right cleanroom wipe directly impacts compliance, product quality, and overall environmental control.
Cleanroom wipes are available in a range of materials and configurations designed for specific applications. Common options include polyester wipes for low-lint, low-extractable performance in critical areas, and poly-cellulose blends for more general cleaning tasks in ISO 7–8 environments. Pre-saturated cleanroom wipes—typically with isopropyl alcohol (IPA) or hydrogen peroxide—provide consistent disinfection and reduce variability in manual saturation. Sterile cleanroom wipes, often gamma-irradiated, are required for aseptic processing and USP <797>/<800> compliant environments where microbial control is critical.
When selecting cleanroom wipes, it’s important to consider factors such as ISO classification, sterility requirements, compatibility with cleaning agents, and the specific surfaces being cleaned. High-performance wipes are engineered to minimize particle shedding, resist abrasion, and maintain chemical purity, helping to prevent cross-contamination. By matching the wipe type to your application, you can improve cleaning effectiveness, support regulatory compliance, and maintain the integrity of your controlled environment.
Types of Cleanroom Wipes By Material & Application
Not sure which cleanroom wipe is right for your application? Use the guide below to quickly identify the best option based on your environment and use case.
| Material Type | Typical ISO Class | Most Common Uses |
|---|---|---|
| Polyester Wipes | ISO 3–5 | Critical cleaning, cleanest of wipe materials, delicate surfaces |
| Microfiber Wipes | ISO 4–6 | Fine particle removal, polishing, sensitive surfaces, deep cleaning |
| Foam Wipes | ISO 5–7 | Applying disinfectants, absorbing liquids, cleaning irregular surfaces |
| Nonwoven Wipes | ISO 6–8 | General cleaning, spill control, maintenance, cleanroom paper towels |
| 2-Ply Quilted Wipes | ISO 5–8 | Absorbent cleaning, spill pickup, heavy-duty cleaning |
| Pre-Saturated Alcohol Wipes | ISO 5–7 | Surface disinfection, routine wipe-downs |
| Pre-Saturated Wipes (Bleach, Peroxide, etc) | ISO 5–7 | Convenience in not having to saturate wipes, consistent saturation |
| Sterile Polyester Wipes | ISO 3–5 | Cleanest of the sterile wipe options |
| Sterile Wipes | ISO 3–5 | Wiping down sterile surfaces, multiple materials available |
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70% Isopropyl Alcohol Wipes12 Products
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Cleanroom Disinfectant Wipes9 Products
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Criti Clean Wipes7 Products
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ESD Anti-Static Wipes1 Product
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Foam Cleanroom Wipes1 Product
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Hydroflex PurWipes6 Products
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Microfiber Cleanroom Wipes2 Products
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Nonwoven Cleanroom Wipes5 Products
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Polyester Cleanroom Wipes5 Products
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Quilted Cleanroom Wipes3 Products
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Sterile Cleanroom Wipes12 Products
Biomedix Lint-Free Sterile Cleanroom Wipe
TrueCare sterile lint free cleanroom wipes are our customers’ favorite sterile dry cleanroom wiper. They are super absorbent, extra durable, and economical. Accompanied by a certificate assuring gamma sterilization. These wipes are widely are used in medical device manufacturing, USP compounding pharmacies, as well as cGMP pharmaceutical manufacturing.
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- Sterile
- Nonwoven blend of 55% cellulose and 45% polyester
- Most popular sterile lint-free wipe
- 9″x9″, 12 bags of 300 or in 180 bags of 20
- 12″x12″, 8 bags of 150 or in 60 bags of 20 wipes
- Class 1000 ISO6+
Biomedix Sterile 4×4 Nonwoven Alcohol Wipe
True Care TCBWALC6004 sterile isopropyl alcohol cleanroom wipes are lint-free and safe for use in your ISO5+ critical environments. These wipes are 4″x4″ which is an efficient size for cleaning vials and small items. They are made of ultra-clean nonwoven polyester which has a smooth cloth texture, is lint-free and extremely durable.
- Sterile
- 4″x4″ size
- Nonwoven polyester
- 70% USP Grade IPA / 30% DI water
- 1440 wipes, 24 pouches of 60 wipes
- Class 100 ISO5+ compatible
- Thicker than other pre-wetted wipes for added durability and absorption
- Tear proof, soft cloth texture will not scratch any surfaces
Biomedix Sterile 4×4 Polyester Alcohol Wipe
True Care TCBWALC1204 sterile isopropyl alcohol cleanroom wipes are lint-free and safe for use in your ISO4-5 critical environments. These wipes are 4″x4″ which is an efficient size for cleaning vials and small items. They are made of ultra-clean polyester which has a smooth cloth texture, is lint-free and extremely durable.
- Sterile
- 4″x4″ size
- 70% USP Grade IPA / 30% DI water
- 1440 wipes, 24 pouches of 60 wipes
- Class 10-100 ISO4-5 compatible
- Thicker than other pre-wetted wipes for added durability and absorption
- Tear proof, soft cloth texture will not scratch any surfaces
BioMedix Sterile Alcohol Wipe
True Care Sterile 70% IPA presaturated cleanroom wipes are our top selling sterilized presaturated cleanroom wipe. The nonwoven wipe is presaturated with sterile 70% isopropyl alcohol, 30% DI water and measures 9 inches by 9 inches. They come in thick plastic pouches with a plastic spring hinged side door that seals shut automatically. You open the door, remove a wipe and the door closes. Each pouch comes double bagged.
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- Most popular sterile prewetted cleanroom wipe
- Prewetted with 70% IPA / 30% DI water
- 9″x9″ Size
- 720 wipes, 24 packs of 30 wipes
- Class 1000 ISO6 and higher rated
- Ready to use, saturated
- Sterile
- Plastic bag door automatically closes
CaviWipes 2.0 Disinfectant Wipe
Caviwipes 2.0 surface disinfectant wipes kill 60 pathogens within a 2-minute kill time and also qualifies for the EPA Emerging Viral Pathogen qualification. The duckbill easy-open top is convenient, as are the color-coded top and no-tear opening to remove one wipe at a time. Choose from two sizes depending on your cleaning job.
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- Non-sterile
- Kills 60 listed pathgens in 2 minutes
- One-step easy to use disinfectant wipe
- No-tear opening, remove one wipe at a time
- Most popular disinfectant wipe for labs and healthcare
- 12 canisters per case
CaviWipes Bleach Wipe
CaviWipes Bleach disinfecting wipes are a patented multi-purpose cleaning wipe that is gentle on surfaces, yet tough on pathogens. They kill C. diff spores in 3 minutes and do not require PPE when handling. These non-shedding bleach wipes also meet the CDC recommended 1:10 bleach dilution and are compatible with most medical device equipment. CaviWipes Bleach wipes also fully qualify for the EPA Emerging Viral Pathogen (EVP Level III) Claim for all virus types including enveloped, large and small non-enveloped viruses to meet current and future infection prevention needs.
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- Non-sterile
- Low odor
- Great general purpose disinfectant wipe
- 12 canisters per case
- No gloves needed
- Class 1000+ ISO6-8+ compatible
- Ideal 6″x10″5 size for flexible cleaning needs
- 3-Min universal contact time against 43 relevant pathogens including C. Diff, TB, C. auris, Norovirus, and 8 MDROs (Multidrug Resistant Organisms)
CaviWipes HP Hydrogen Peroxide Wipe
CaviWipes HP hydrogen peroxide disinfecting wipes provide a 1-minute universal contact time from a hydrogen peroxide formulation that qualifies for the EPA’s rigorous Emerging Viral Pathogen Claim. The High Performance disinfection protocol offered by CaviWipes HP helps protect both patients and staff. In addition to providing effective disinfection against all 67 listed pathogens including multidrug resistant organisms, the use of gloves is not required when using these wipes.
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- Non-sterile
- 12 canisters per case
- 1 minute efficacy against 67 listed pathogens
- Class 1000+ ISO6-8+ compatible
- Choose from 6″x6.75″ or 9″x12″
- Extremely effective multi-purpose disinfectant wipe
Cidehol Isopropyl Alcohol Wipe
Decon Labs 8776 Cidehol 70 alcohol wipes are one of our most popular non-sterile alcohol wipes that are lint-free. These wipes are smaller at 6″x6″ size, but they are very tough and great for scrubbing. The non-linting wipes are a convenient alternative to spraying Cidehol ST 70 IPA or other IPA products. You pull them out of the the white canister and the wipes are attached to each other. This enables you to make one larger wipe consisting of 2-3 wipes. The canister is sealed, keeping the wipes nice and moist.
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- Non-sterile
- 6″x7″ size
- 12 canisters of 175 wipes
- Durable white plastic canister
- Lint-free nonwoven wipe material
- USP-Grade 70% isopropyl alcohol
- Safe for use on all surfaces including sensitive surfaces that are easily scratched
- Made in the USA
Clean-Quilt Polyester Quilted Cleanroom Wipe
Criti Clean Clean-Quilt Polyester 2-Ply quilted cleanroom wipes are constructed with two layers of virgin interlock knitted polyester. These wipes have been cleanroom laundered before being double bagged. We recommend these wipes for deep cleaning applications in ISO 5 environments that need a lot of absorption or extra scrubbing durability. Since these wipes consist of 2 layers they can absorb a large amount of fluid. They are abrasion resistant and will not shed any particles. If working in a less strict environment, we recommend our low-linting nonwoven wipes.
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- Non-sterile
- 9″x9″ size
- Laser cut sealed edge
- Class 10-100 ISO4-5+
- Quilted, 2-ply
- Ultrasonically joined layers
- Extra absorption
Clean-Quilt Polypropylene Quilted Cleanroom Wipe
Criti Clean Clean-Quilt Nonwoven 2-Ply quilted cleanroom wipes are made with two heat-bonded layers. One layer is cellulose and then a layer of polypropylene that has been clean-processed and heat bonded together to form an ultra-absorptive lint free wipe. These wipes absorb a lot, they are like two wipes in one. These wipes are extra thick and the polypropylene layer adds durability when cleaning and scrubbing. If a higher cleanliness level is needed, see our cleaner polyester quilted wipe.
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- Non-sterile
- Economical
- 8″x8″ or 11″x12″ sizes
- Class 1000+ ISO6
- Extra absorptive
- Very durable
- Polypropylene & cellulose layers
- Lint-free
Clean-Stat Anti-Static Cleanroom Wipe
Criti Clean Clean-Stat antistatic polyester cleanroom wipes are comprised of a patented blend of ultra-washed laundered polyester and strands of conductive carbon fiber. The anti-static wipes prevent build up of electrostatic charge via the carbon fiber strands that dissipate it from work surfaces, equipment, and components under construction.
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- 9″x9″ size
- Class 100 ISO5
- Laundered to remove any particles
- Ultra-soft, will not scratch
- Double-bagged in a cleanroom enviornment
- Made in the USA
Criti Clean Foam Cleanroom Wipe
Criti Clean Clean-Foam sponge wipers are excellent for applying solutions as well as soaking up spills. They are a favorite wipe for many controlled environment applications where a soft and super-absorbent wipe with exceptionally low particle generation is needed. These sponge wipes can be used with most cleanroom cleaning chemicals and are autoclavable.
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- 6″x9″, 9″x9″, 12″x12″ sizes
- Class 1000+ ISO6
- Absorbs 30x weight in liquid
- Great for applying liquids
- Amazing for spills
- Autoclavable